Shutong Li

About

I am a PhD candidate in Craniofacial Biology at University of Southern California. My advisor is Porf. Pinghui Feng. I obtained my Bachelor and Master degrees of Stomatology at Shandong University. My advisor was Prof. Pishan Yang, and I was also closely collaborating with Prof. Shaohua Ge and Prof. Yundong Sun. My research interests are in bacterial-virus interaction within the human oral cavity.

My recent projects:

• Roles of ISG15 in Bacteria-herpesvirus Interaction in Periodontitis

Publications

• Oral Neisseria gonorrhoeae Promotes KSHV Lytic Replication
  Feng S, Fu W, Li S, Yeh W, She R, Brenner C, Chen C, Feng P
  Journal of Medical Virology, 2025
  [journal]
• Cryptic phosphoribosylase activity of NAMPT restricts the virion incorporation of viral proteins
  Feng S, Xie N, Liu Y, Qin C, Savas A, Wang T, Li S, Rao Y, Shambayate A, Chou T, Brenner C, Huang C, Feng P
  Nature Metabolism, 2024
  [journal]
• Enhanced fatty acid biosynthesis by Sigma28 in stringent responses contributes to multidrug resistance and biofilm formation in Helicobacter pylori
  Xue J, Li S, Wang L, Zhao Y, Zhang L, Zheng Y, Zhang W, Chen Z, Jiang T, Sun Y
  Antimicrobial Agents and Chemotherapy, 2024
  [journal]
• Low-dose TNF-α promotes angiogenesis of oral squamous cell carcinoma cells via TNFR2/Akt/mTOR axis
  Li S, Liu W, Liu J, Yang Z, Zhang L, Nie F, Yang P, Guo H, Yang C
  Oral Diseases, 2024
  [journal]
• PGRN is involved in macrophage M2 polarization regulation through TNFR2 in periodontitis
  Zhang L, Nie F, Zhao J, Li S, Liu W, Guo H, Yang P
  Journal of Translational Medicine, 2024
  [journal]
• M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation
  Lv C, Li S, Zhao J, Yang P, Yang C
  ACS omega, 2022
  [journal]
• Helicobacter pylori infection is correlated with the incidence of erosive oral lichen planus and the alteration of the oral microbiome composition
  Li S^*, Zhang Y^*, Li J, Li Y, Li H, Li W, Jia J, Ge S, Sun Y
  BMC Microbiology, 2021
  [journal]
• Progranulin inhibits LPS-induced macrophage M1 polarization via NF-κB and MAPK pathways
  Liu L, Guo H, Song A, Huang J, Zhang Y, Jin S, Li S, Zhang L, Yang C, Yang P
  BMC Immunology, 2020
  [journal]
• Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway
  Huang J, Liu L, Jin S, Zhang Y, Zhang L, Li S, Song A, Yang P
  Inflammation, 2020
  [journal]
• Conditioned medium derived from FGF-2-modified GMSCs enhances migration and angiogenesis of human umbilical vein endothelial cells
  Jin S, Yang C, Huang J, Liu L, Zhang Y, Li S, Zhang L, Sun Q, Yang P
  Stem Cell Research & Therapy, 2020
  [journal]
• Prolyl hydroxylase inhibitor DMOG suppressed inflammatory cytokine production in human gingival fibroblasts stimulated with Fusobacterium nucleatum
  Shang L, Kang W, Li S, Ge S
  Clinical Oral Investigations, 2019
  [journal]

Presentations

• Bacteria-virus interaction identifies an unexpected role of ISGylation in promoting gamma herpesvirus replication
  [Abstract Award]
  27th International Workshop on Kaposi's Sarcoma Herpesvirus (KSHV) & Related Agents, Redondo Beach, CA, USA, July 2025
  
• Oral Pathogens Drive Gamma Herpesvirus Replication via ISGylation
  The International Association for Dental, Oral, and Craniofacial Research (IADR), Barcelona, Spain, June 2025
  [abstract]
• Periodontal-orthodontic Treatment in Patients with Aggressive Periodontitis: A Case Report
  The Workshop of Periodontology and Implantology at NTU-SDU at Shandong University, Jinan, China, Aug 2018

Awards

• Abstract Award of 27th International Workshop on Kaposi's Sarcoma Herpesvirus (KSHV) & Related Agents
  27th International Workshop on Kaposi's Sarcoma Herpesvirus (KSHV) & Related Agents, 2025
• Provost Fellowship for Incoming Students
  University of Southern California, 2021
• The Award of Skilled Residents
  22nd China Stomatological Association (CSA) Annual Meeting & China Dental Show, 2020
• Graduate Student of the Year
  Shandong University, 2019
• The First Prize Scholarship
  Shandong University, 2019&2017
• Postgraduate Scholarship
  Shandong University, 2018
• The Volunteer Service Outstanding Student
  Shandong University, 2018
• "Relationship and mechanism between Helicobacter pylori and oral lichen planus," $2,242
  National College Student Innovation and Entrepreneurship Foundation, 2017
• "Relationship and mechanism of periodontitis and oral squamous cell carcinoma," $2,242
  National College Student Innovation and Entrepreneurship Foundation, 2016.
• National Excellent Social Practice Project
  "A study on women's awareness of maternal and infant oral care during the pregnancy"
  China Oral Health Foundation, 2015
• Outstanding Overseas Student with Scholarship
  Shandong University, 2015
• Social Practice Excellent Individual
  Shandong University, 2014